Jake Estes, PhD

Dr. Jake Estes obtained his Ph.D. at Brigham Young University in the laboratory of Dr. Gregory Burton studying the contributions of follicular dendritic cells and the germinal center microenvironment to HIV pathogenesis. Dr. Estes continued his work as a postdoctoral fellow in the laboratory of Dr. Ashley Haase in the Department of Microbiology at the University of Minnesota, focusing on the in vivo immunopathology of lentiviral infections in lymphoid tissues in both human patient cohorts and non-human primate models. After his postdoctoral training, Dr. Estes joined the AIDS and Cancer Virus Program (ACVP) at the Frederick National Laboratory for Cancer Research, which performs biomedical research for the National Cancer Institute (NCI), part of the U.S. National Institutes of Health (NIH), where Dr. Estes served as a Senior Principal Scientist and Principal Investigator for 10 years. Dr. Estes is currently a Professor in the Vaccine & Gene Therapy Institute at Oregon Health & Sciences University, and Chief of the Division of Pathobiology and Immunology at the Oregon National Primate Research Center. Dr. Estes’s research focuses on key aspects of lentiviral mucosal transmission, viral persistence and pathogenesis using state-of-the art tissue analysis capabilities to better understand host-viral interactions in vivo following mucosal infection and the immunopathogenic mechanisms and processes driving viral persistence and disease progression.